Human growth hormone (HGH) is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. Some people take HGH supplements claiming they can help reduce inflammation, however, the science behind these claims is inconclusive.
Inflammation is a normal immune response triggered by injury or infection. Acute inflammation lasts for a short time and helps the body heal. Chronic inflammation persists over longer periods and can lead to various diseases. Some causes of chronic inflammation include:
- Autoimmune disorders
- Long-term infections
- Exposure to irritants
- Obesity
HGH and Inflammation Research
Several studies have looked into the links between HGH and inflammation:
- A 2012 study found that giving synthetic HGH injections to mice with inflamed paws reduced swelling and markers of inflammation. The researchers concluded HGH might have "therapeutic potential" for treating inflammatory conditions.
- A small 2014 study in humans found that people with greater inflammatory markers tended to have lower natural HGH levels. This suggests a relationship between low HGH and increased inflammation.
- A 2016 review evaluated using HGH to treat abdominal inflammation after surgery. Results were inconclusive overall, though certain patients showed improvements.
So while some research shows potential anti-inflammatory effects, much more evidence is still needed.
Possible Mechanisms
Researchers theorize a few reasons why HGH supplementation might reduce inflammation:
- HGH may switch immune cells from producing inflammatory compounds to anti-inflammatory ones
- HGH could stimulate tissue regeneration, healing sites of inflammation faster
- Higher HGH levels may counterbalance inflammation-promoting hormones
However, the exact mechanisms are still unclear.
Considerations of HGH Therapy
Before using HGH to tackle inflammation, keep the following limitations in mind:
- HGH research for inflammation is still in early phases
- Effects likely depend on the individual and condition
- Synthetic HGH injections may cause side effects
- Treatment can be expensive and is not widely covered by insurance
Always consult a doctor before starting HGH therapy. Illegal, unregulated HGH supplements can be unsafe.
Lifestyle Approaches to Lowering Inflammation
While HGH shows some promise for inflammation, making healthy lifestyle choices may also help:
- Eating anti-inflammatory foods: Fruits, vegetables, fish, nuts, plant oils, yogurt, and spices like turmeric contain antioxidants and nutrients that combat inflammation. Avoiding excess sugar, processed foods, and saturated fats can also help.
- Exercising regularly: Any moderate physical activity helps lower inflammatory markers.Aim for 30-60 minutes per day.
- Reducing stress: Chronic stress promotes inflammation. Practices like meditation, yoga, journaling, and socializing can relieve stress.
- Getting enough sleep: Not getting 7-9 hours per night is linked with higher inflammation. Prioritizing restful sleep supports health.
Along with speaking to a doctor about concerns with inflammation, adopting an overall healthy lifestyle can make a big difference. HGH therapy could provide additional targeted relief for some patients once further research establishes stronger guidelines for its use.